Sodium Hydroxide → 9,9-Bis(4-pyridinylmethyl)-2-fluorofluorene dihydrochloride

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared following the method of Example 1 from 4.0 g (21.74 mmole) of 2-fluorofluorene, 8.92 g of 4-picolylchloride hydrochloride, 120 ml of toluene, 200 mg of benzyltriethylammonium chloride, and 20 ml of 50% sodium hydroxide by reaction at 22° for 17 hrs. The product was chromatographed (silica, CH2Cl2 /MeOH,10:1) to yield 2.9 g which was recrystallized (ethanol-acetone) and converted to the dihydrochloride, m.p. >300°.

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