HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxygen → HCID 57215923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxygen | HCID 977 | — |
| Reactant | Pregnenolone | HCID 8955 | — |
| Product | HCID 57215923 | HCID 57215923 | — |
Reaction Steps
3β-Hydroxy-5-pregnen-20-one 1 reacts with singlet oxygen to yield 5α-hydroperoxy-3β-hydroxy-6-pregnene-20-one 2. This hydroperoxide undergoes a rearrangement when in chloroform solution to yield 7α-hydroperoxy-3β-hydroxy-5-pregnene-17-one, 3. Treatment of the hydroperoxide with zinc and acetic acid yields 3β,7α-dihydroxy-5-pregnen-20-one 4. ##STR27##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175154 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-cf2b2a93d4284d0c9302bf71625ae1b2 |
| Source note | uspto-grants-1992_12 |