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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681817Generated: October 30, 2026

11-(Chloroacetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one → AQ-RA 741

https://huagongshe.com/reaction/1681817

Reaction equation

Participants

RoleNameHCIDCharge
Reactant11-(Chloroacetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oneHCID 120053—
Reactant4-Piperidinebutanamine, N,N-diethyl-HCID 10081918—
ProductAQ-RA 741HCID 12998943%

Reaction Steps

Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[4-(diethylamino)butyl]piperidine in a yield of 43% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175158
Source datasetuspto-grants-1992_12
ORD IDord-ca97425a61d04ce78dfa4b17a27bb2b7
Source noteuspto-grants-1992_12