HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 1-Methyl-5-methoxycarbonylpyrimidinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Methyl pyrimidine-5-carboxylate | HCID 253902 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Methyl-5-methoxycarbonylpyrimidinium iodide | HCID 20080423 | — |
Reaction Steps
5-Methoxycarbonylpyrimidine (597 mg, 4.3 mmol) and methyliodide (1.6 ml, 26 mmol) were dissolved in acetonitrile (20 ml) in a stoppered flask and stirred at room temperature. After five days diethyl ether was added to precipitate red crystalline product 314 mg (26%), mp 167°-170° C. with effervescence. Calculated: C 30.02, H 3.24, N 10.00; found: C 29.88, H 3.30, N 10.07.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175166 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-ef3703cc016f4b0198147aa4b0a66edc |
| Source note | uspto-grants-1992_12 |