Methyl iodide → HCID 19804285, compound

Participants

Reaction Steps

5-(1,3-oxathiolan-2-yl)pyrimidine (0.780 g, 5.1 mmol) and acetonitrile (3 ml) are stirred under dry nitrogen in a bomb tube with rubber seal. Methyl iodide (0.7 ml, 11.30 mmol) is added, the bomb properly sealed, and stirring continued at room temperature overnight. This results in a yellow suspension which is vacuum-filtered to obtain yellow powdery crystals. The powder is put in a drying pistol to give 1.32 g (84%) yellow crystals. Recrystallization from ethanol gives fine crystals identified by 300 MHz nmr.

Provenance & Evidence