3,5-Dimethyl-4-hydroxybenzonitrile → HCID 136034837, compound

Participants

Reaction Steps

By following a procedure similar to that described in Example 1(a) but substituting for the 3,5-dimethyl-4-hydroxybenzonitrile an equimolar amount of the compound from Example 8, part (d), there can be obtained 3-[4-(3-ethinylpropoxy)-2-hydroxy-3-methylphenyl]-5-methyl-1,2,4-oxadiazole and its positional isomer 3-[2-(3-ethinylpropoxy)-4-hydroxy-3-methylphenyl]-5-methyl-1,2,4-oxadiazole which can be separated by conventional procedures.

Provenance & Evidence