5-(5-Bromopentyl)-3-methylisoxazole → HCID 15057283, compound
Reaction equation
[O:1]1[C:5]([C:6]2[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=2)=[N:4][CH:3]=[N:2]1.Br[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]1[O:23][N:22]=[C:21]([CH3:24])[CH:20]=1>>[O:1]1[C:5]([C:6]2[CH:11]=[CH:10][C:9]([O:12][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[O:23][N:22]=[C:21]([CH3:24])[CH:20]=3)=[CH:8][CH:7]=2)=[N:4][CH:3]=[N:2]1Participants
3
Procedure
It is further contemplated that 4-(1,2,4-oxadiazol-5-yl)phenol can be caused to react with 5-(5-bromopentyl)-3-methylisoxazole according to the procedure of Example 1 to give 5-{5-[4-(1,2,4-oxadiazol-5-yl)phenoxy]pentyl}-3-methylisoxazole [II; R1 and R2 =H, Het=1,2,4-oxadiazol-5-yl].
Sources & evidence
- ORD record
- ord-26f3b46d924e49afbdbbd3efb977fef0
- Source dataset
- uspto-grants-1992_12
- Patent number
- US05175178
Reaction notes
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