HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 1-(tert-Butyl)-3-ethynylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-tert-Butylphenylacetylene | HCID 2757302 | — |
| Reactant | (3-tert-Butyl-phenylethynyl)-trimethyl-silane | HCID 14989665 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(tert-Butyl)-3-ethynylbenzene | HCID 14989667 | — |
Reaction Steps
Using the same general procedure as described for Compound 19), but using instead trimethylsilyl (3-tert-butyl) phenylethyne (Compound 25) and aqueous KOH in methanol, the title compound was synthesized as a colorless oil. PMR (CDCl3) & 1.29 (9H, s), 3.03 (1H, s), 7.22 (1H, t, J~7.5 Hz), 7.30 (1H, dt, J~7.5 Hz, 1.5 Hz), 7.36 (1H, dt, J~7.5 Hz, 1.5Hz), 7.53 (1H,t, J~1.5 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175185 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-b6b8a9e52b7941d2a47386e67ecaa462 |
| Source note | uspto-grants-1992_12 |