3-(3-Methoxyphenoxy)-propyl chloride → 3-[(N-(3-(3-Methoxy-phenoxy)-propyl)-piperidin-3-yl)methyl]-7,8-methylenedioxy-1,3,4, 5-tetrahydro-2H-3-benzazepin-2-one

HRID 1682014Notes

Reaction equation

HRID 1682014 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[C:14](=[O:15])[CH2:13][C:12]3[CH:16]=[C:17]4[O:22][CH2:21][O:20][C:18]4=[CH:19][C:11]=3[CH2:10][CH2:9]2)[CH2:2]1.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([CH:33]=[CH:34][CH:35]=1)[O:28][CH2:29][CH2:30][CH2:31]Cl>>[CH3:23][O:24][C:25]1[CH:26]=[C:27]([CH:33]=[CH:34][CH:35]=1)[O:28][CH2:29][CH2:30][CH2:31][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[C:14](=[O:15])[CH2:13][C:12]3[CH:16]=[C:17]4[O:22][CH2:21][O:20][C:18]4=[CH:19][C:11]=3[CH2:10][CH2:9]2)[CH2:2]1

Participants

3

Reactant 2

HCID 167929103-(3-Methoxyphenoxy)-propyl chlorideHCID 543405853-[(piperidin-3-yl)-methyl]-7,8-methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one

Product 1

HCID 198036863-[(N-(3-(3-Methoxy-phenoxy)-propyl)-piperidin-3-yl)methyl]-7,8-methylenedioxy-1,3,4, 5-tetrahydro-2H-3-benzazepin-2-one

Procedure

Prepared from 3-[(piperidin-3-yl)-methyl]-7,8-methylenedioxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one and 3-(3-methoxyphenoxy)-propyl chloride analogously to Example 1.

Sources & evidence

ORD record
ord-be4e8db63191469ab9ac58df926161c3
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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