HCID 19803459, compound → HCID 14306680, compound

HRID 1682026Notes

Reaction equation

HRID 1682026 reaction equation
[NH:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]([CH2:8][N:9]2[CH2:18][CH2:17][C:16]3[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=3)[C:10]2=[O:23])[CH2:2]1.Br[CH2:25][CH2:26][C:27]1[CH:36]=[CH:35][C:34]2[C:29](=[CH:30][CH:31]=[C:32]([O:38][CH3:39])[C:33]=2[CH3:37])[CH:28]=1>>[CH3:37][C:33]1[C:32]([O:38][CH3:39])=[CH:31][CH:30]=[C:29]2[C:34]=1[CH:35]=[CH:36][C:27]([CH2:26][CH2:25][N:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]([CH2:8][N:9]3[CH2:18][CH2:17][C:16]4[C:11](=[CH:12][C:13]([O:21][CH3:22])=[C:14]([O:19][CH3:20])[CH:15]=4)[C:10]3=[O:23])[CH2:2]1)=[CH:28]2

Participants

3

Reactant 2

HCID 19803459HCID 19803459, compoundHCID 19804144HCID 19804144, compound

Product 1

HCID 14306680HCID 14306680, compound

Procedure

Prepared from 2-[(hexahydro-azepin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 2-(2-bromoethyl)-5-methyl-6-methoxy-naphthalene analogously to Example 1.

Sources & evidence

ORD record
ord-3402f15857d74cd5be8561758dcf9998
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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