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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682030Generated: November 3, 2026

1-(3-Chloropropoxy)-3-methylbenzene → 2-[2-(N-(3-(3-Methyl-phenoxy)-propyl)-piperid-2-yl)-ethyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

https://huagongshe.com/reaction/1682030

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chloropropoxy)-3-methylbenzeneHCID 12760306—
Reactant2-[2-(Piperid-2-yl)-ethyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinolineHCID 19803701—
Product2-[2-(N-(3-(3-Methyl-phenoxy)-propyl)-piperid-2-yl)-ethyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochlorideHCID 19803747—

Reaction Steps

Prepared from 2-[2-(piperid-2-yl)-ethyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 1-chloro-3-(3-methyl-phenoxy)-propane analogously to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175157
Source datasetuspto-grants-1992_12
ORD IDord-84924f095aba4f6a8df3519172b2382f
Source noteuspto-grants-1992_12