HCID 14306655, compound → 2-[(N-(3-(3,5-Dimethoxy-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

HRID 1682034Notes

Reaction equation

HRID 1682034 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1.[Cl:23][CH2:24][CH2:25][CH2:26][O:27][C:28]1[CH:33]=[C:32]([O:34][CH3:35])[CH:31]=[C:30]([O:36][CH3:37])[CH:29]=1>>[ClH:23].[CH3:35][O:34][C:32]1[CH:33]=[C:28]([CH:29]=[C:30]([O:36][CH3:37])[CH:31]=1)[O:27][CH2:26][CH2:25][CH2:24][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1

Participants

3

Reactant 2

HCID 14306655HCID 14306655, compoundHCID 144071741-(3-Chloropropoxy)-3,5-dimethoxybenzene

Product 1

HCID 198038942-[(N-(3-(3,5-Dimethoxy-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

Procedure

Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 1-chloro-3-(3,5-dimethoxy-phenoxy)-propane analogously to Example 1.

Sources & evidence

ORD record
ord-8a1b70bcb7ca446f96c04f9e1d7f30a5
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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