HCID 14306655, compound → 2-[(N-(3-(2,6-Dimethyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

HRID 1682035Notes

Reaction equation

HRID 1682035 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1.[Cl:23][CH2:24][CH2:25][CH2:26][O:27][C:28]1[C:33]([CH3:34])=[CH:32][CH:31]=[CH:30][C:29]=1[CH3:35]>>[ClH:23].[CH3:35][C:29]1[CH:30]=[CH:31][CH:32]=[C:33]([CH3:34])[C:28]=1[O:27][CH2:26][CH2:25][CH2:24][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:17][CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:20][CH3:21])=[C:13]([O:18][CH3:19])[CH:14]=3)[C:9]2=[O:22])[CH2:2]1

Participants

3

Reactant 2

HCID 14306655HCID 14306655, compoundHCID 147153542-(3-Chloropropoxy)-1,3-dimethylbenzene

Product 1

HCID 198035882-[(N-(3-(2,6-Dimethyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

Procedure

Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-dimethoxy- 1-oxo-1,2,3,4-tetrahydro-isoquinoline and 1-chloro-3-(2,6-dimethylphenoxy)-propane analogously to Example 1.

Sources & evidence

ORD record
ord-908209cbdc9642579c6d925c3a9b10e8
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

Loading…