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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682038Generated: November 3, 2026

4-(2-Chloroethyl)phenyl methyl ether → 2-[(N-(2-(4-Methoxy-phenyl)-ethyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

https://huagongshe.com/reaction/1682038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Chloroethyl)phenyl methyl etherHCID 87513—
Reactant2-[(Piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinolineHCID 19803711—
Product2-[(N-(2-(4-Methoxy-phenyl)-ethyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochlorideHCID 19803902—

Reaction Steps

Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-methylenedioxy- 1-oxo-1,2,3,4-tetrahydro-isoquinoline and 1-chloro-2-(4-methoxy-phenyl)-ethane analogously to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175157
Source datasetuspto-grants-1992_12
ORD IDord-80d65bd01fc84c4ea3ed68a11b94d84e
Source noteuspto-grants-1992_12