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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682041Generated: November 2, 2026

1-(3-Chloropropoxy)-3-methylbenzene → 2-[(N-(3-(3-Methyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochloride

https://huagongshe.com/reaction/1682041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chloropropoxy)-3-methylbenzeneHCID 12760306—
Reactant2-[(Piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinolineHCID 19803711—
Product2-[(N-(3-(3-Methyl-phenoxy)-propyl)-piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline-hydrochlorideHCID 19803562—

Reaction Steps

Prepared from 2-[(piperidin-3-yl)-methyl]-6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 3-(3-methyl-phenoxy)-1- chloro-propane analogously to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175157
Source datasetuspto-grants-1992_12
ORD IDord-436252afa1624f38a22e89941abb1e96
Source noteuspto-grants-1992_12