HCID 14306828, compound → HCID 14306830, compound

HRID 1682043Notes

Reaction equation

HRID 1682043 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]2[CH2:16][CH2:17][N:18]2[CH2:26][C:25]3[C:20](=[CH:21][C:22]([CH3:28])=[C:23]([CH3:27])[CH:24]=3)[C:19]2=O)=[CH:3][CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1.CCOCC>[N:1]1[CH:2]=[CH:3][C:4]([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]2[CH2:16][CH2:17][N:18]2[CH2:19][C:20]3[C:25](=[CH:24][C:23]([CH3:27])=[C:22]([CH3:28])[CH:21]=3)[CH2:26]2)=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 14306828HCID 14306828, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 14306830HCID 14306830, compound

Reagents, catalysts & solvents 1

HCID 21868444Ether tetrahydrofuranSolvent

Procedure

Prepared from 2-[2-(N-(3-(pyrid-4-yl)-propyl)-piperid-2-yl)-ethyl]-5,6-dimethyl-1-oxo-1,3-dihydro-isoindole and lithium aluminium hydride in tetrahydrofuran/ether analogously to Example 3.

Sources & evidence

ORD record
ord-17faff19f62e4e34ab38e8deda485658
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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