HCID 19803952, compound → HCID 19804178, compound

HRID 1682046Notes

Reaction equation

HRID 1682046 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][N:10]2[CH2:19][CH2:18][C:17]3[C:12](=[CH:13][C:14]([O:22][CH3:23])=[C:15]([O:20][CH3:21])[CH:16]=3)[C:11]2=[O:24])[CH:2]=1.[Cl:25][CH2:26][CH2:27][C:28]1[C:37]2[C:32](=[CH:33][C:34]([O:40][CH3:41])=[C:35]([O:38][CH3:39])[CH:36]=2)[CH:31]=[N:30][CH:29]=1>>[OH2:20].[ClH:25].[ClH:25].[CH3:39][O:38][C:35]1[CH:36]=[C:37]2[C:32](=[CH:33][C:34]=1[O:40][CH3:41])[CH:31]=[N:30][CH:29]=[C:28]2[CH2:27][CH2:26][N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][CH2:8][CH2:9][N:10]2[CH2:19][CH2:18][C:17]3[C:12](=[CH:13][C:14]([O:22][CH3:23])=[C:15]([O:20][CH3:21])[CH:16]=3)[C:11]2=[O:24])[CH2:2]1

Participants

3

Reactant 2

HCID 19803952HCID 19803952, compoundHCID 19804034HCID 19804034, compound

Product 1

HCID 19804178HCID 19804178, compound

Procedure

Prepared from 2-[3-(pyrid-3-yl)-propyl]-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 4-(2-chloroethyl)-6,7-dimethoxy-isoquinoline analogously to Example 1.

Sources & evidence

ORD record
ord-e3516ac1214e4e10be5bc5454e3b0877
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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