1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one → HCID 67917876, compound

HRID 1682054Notes

Reaction equation

HRID 1682054 reaction equation
[CH3:1][O:2][C:3]1[C:14]([O:15][CH3:16])=[CH:13][C:6]2[CH2:7][C:8](=[O:12])[NH:9][CH:10]=[CH:11][C:5]=2[CH:4]=1.[Cl:17][CH2:18][CH2:19][CH2:20][CH:21]1[CH2:26][CH2:25][CH2:24][N:23]([CH2:27][CH2:28][CH2:29][C:30]2[CH:31]=[N:32][CH:33]=[CH:34][CH:35]=2)[CH2:22]1>>[OH2:2].[ClH:17].[ClH:17].[N:32]1[CH:33]=[CH:34][CH:35]=[C:30]([CH2:29][CH2:28][CH2:27][N:23]2[CH2:24][CH2:25][CH2:26][CH:21]([CH2:20][CH2:19][CH2:18][N:9]3[C:8](=[O:12])[CH2:7][C:6]4[CH:13]=[C:14]([O:15][CH3:16])[C:3]([O:2][CH3:1])=[CH:4][C:5]=4[CH:11]=[CH:10]3)[CH2:22]2)[CH:31]=1

Participants

3

Reactant 2

HCID 14823731,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-oneHCID 19803829HCID 19803829, compound

Product 1

HCID 67917876HCID 67917876, compound

Procedure

Prepared from 7,8-dimethoxy-2-oxo-1,3-dihydro-2H-3-benzazepine and 3-(3-chloropropyl)-N-[3-(pyrid-3-yl)-propyl]-piperidine analogously to Example 2.

Sources & evidence

ORD record
ord-6f6afb7c445645a68b002adf9c826dc6
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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