4-Methylphenethyl bromide → HCID 14306837, compound
Reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]2[CH2:16][C:15]3[C:10](=[CH:11][C:12]([O:19][CH3:20])=[C:13]([O:17][CH3:18])[CH:14]=3)[C:9]2=[O:21])[CH2:2]1.[CH3:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH2:30]Br)=[CH:25][CH:24]=1>>[CH3:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH2:30][N:1]2[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][N:8]3[CH2:16][C:15]4[C:10](=[CH:11][C:12]([O:19][CH3:20])=[C:13]([O:17][CH3:18])[CH:14]=4)[C:9]3=[O:21])[CH2:2]2)=[CH:25][CH:24]=1Participants
3
Procedure
Prepared from 2-[(piperidin-3-yl)-methyl]-5,6-dimethoxy-1-oxo-isoindole and 2-(4-methyl-phenyl)-ethyl bromide analogously to Example 1.
Sources & evidence
- ORD record
- ord-34f2e73ca8994721a90b1f39344ecc20
- Source dataset
- uspto-grants-1992_12
- Patent number
- US05175157
Reaction notes
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