7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one → HCID 67917948, compound

HRID 1682067Notes

Reaction equation

HRID 1682067 reaction equation
[CH3:1][O:2][C:3]1[C:14]([O:15][CH3:16])=[CH:13][C:6]2[CH2:7][C:8](=[O:12])[NH:9][CH2:10][CH2:11][C:5]=2[CH:4]=1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH2:27][CH2:28][N:29]2[CH2:35][CH2:34][CH2:33][CH2:32][CH:31]([CH2:36][Cl:37])[CH2:30]2)[CH:22]=[CH:23][C:24]=1[O:25][CH3:26]>>[ClH:37].[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH2:27][CH2:28][N:29]2[CH2:35][CH2:34][CH2:33][CH2:32][CH:31]([CH2:36][N:9]3[C:8](=[O:12])[CH2:7][C:6]4[CH:13]=[C:14]([O:15][CH3:16])[C:3]([O:2][CH3:1])=[CH:4][C:5]=4[CH2:11][CH2:10]3)[CH2:30]2)[CH:22]=[CH:23][C:24]=1[O:25][CH3:26]

Participants

3

Reactant 2

HCID 114017697,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneHCID 19803860N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-chloromethyl-hexahydro-azepine

Product 1

HCID 67917948HCID 67917948, compound

Procedure

Prepared from 7,8-dimethoxy-1,3,4,5-tetrahydro-2-oxo-3-benzazepine and N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-chloromethyl-hexahydro-azepine analogously to Example 2.

Sources & evidence

ORD record
ord-6c9027e83d404977a87dc196e6e7253e
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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