5,7,8,9-tetrahydro-6H-[1,3]dioxolo[4,5-h][3]benzazepin-6-one → HCID 67918120, compound

HRID 1682068Notes

Reaction equation

HRID 1682068 reaction equation
[CH2:1]1[O:15][C:14]2[C:3](=[CH:4][C:5]3[CH2:11][CH2:10][NH:9][C:8](=[O:12])[CH2:7][C:6]=3[CH:13]=2)[O:2]1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH2:26][CH2:27][N:28]2[CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([CH2:35][Cl:36])[CH2:29]2)[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]>>[ClH:36].[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH2:26][CH2:27][N:28]2[CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([CH2:35][N:9]3[C:8](=[O:12])[CH2:7][C:6]4[CH:13]=[C:14]5[O:15][CH2:1][O:2][C:3]5=[CH:4][C:5]=4[CH2:11][CH2:10]3)[CH2:29]2)[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]

Participants

3

Reactant 2

HCID 130925095,7,8,9-tetrahydro-6H-[1,3]dioxolo[4,5-h][3]benzazepin-6-oneHCID 19803860N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-chloromethyl-hexahydro-azepine

Product 1

HCID 67918120HCID 67918120, compound

Procedure

Prepared from 7,8-methylenedioxy-1,3,4,5-tetrahydro-2-oxo-3-benzazepine and N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-chloromethyl-hexahydro-azepine analogously to Example 2.

Sources & evidence

ORD record
ord-32c1d88964e940c8bd63fbe78c1bd2b6
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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