5,7,8,9-tetrahydro-6H-[1,3]dioxolo[4,5-h][3]benzazepin-6-one → 3-[(N-(3-(3,4-Methylenedioxy-phenoxy)-propyl)-hexahydroazepin-3-yl)-methyl]-7,8-methylenedioxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine-hydrochloride

HRID 1682070Notes

Reaction equation

HRID 1682070 reaction equation
[CH2:1]1[O:15][C:14]2[C:3](=[CH:4][C:5]3[CH2:11][CH2:10][NH:9][C:8](=[O:12])[CH2:7][C:6]=3[CH:13]=2)[O:2]1.[CH2:16]1[O:37][C:36]2[CH:35]=[CH:34][C:20]([O:21][CH2:22][CH2:23][CH2:24][N:25]3[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]([CH2:32][Cl:33])[CH2:26]3)=[CH:19][C:18]=2[O:17]1>>[ClH:33].[CH2:16]1[O:37][C:36]2[CH:35]=[CH:34][C:20]([O:21][CH2:22][CH2:23][CH2:24][N:25]3[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]([CH2:32][N:9]4[C:8](=[O:12])[CH2:7][C:6]5[CH:13]=[C:14]6[O:15][CH2:1][O:2][C:3]6=[CH:4][C:5]=5[CH2:11][CH2:10]4)[CH2:26]3)=[CH:19][C:18]=2[O:17]1

Participants

3

Reactant 2

HCID 130925095,7,8,9-tetrahydro-6H-[1,3]dioxolo[4,5-h][3]benzazepin-6-oneHCID 19803892HCID 19803892, compound

Product 1

HCID 679177493-[(N-(3-(3,4-Methylenedioxy-phenoxy)-propyl)-hexahydroazepin-3-yl)-methyl]-7,8-methylenedioxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine-hydrochloride

Procedure

Prepared from 7,8-methylenedioxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine and N-[3-(3,4-methylenedioxy-phenoxy)-propyl]-3-chloromethyl-hexahydro-azepine analogously to Example 2.

Sources & evidence

ORD record
ord-6dc712364b414b64b44f9c5395226805
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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