Corydaldine → HCID 19803826, compound

HRID 1682074Notes

Reaction equation

HRID 1682074 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[C:9](=[O:15])[NH:8][CH2:7][CH2:6]2.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:34]=[CH:35][C:36]=1[O:37][CH3:38])[O:21][CH2:22][CH2:23][CH2:24][N:25]1[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]([CH2:32][Cl:33])[CH2:26]1>>[ClH:33].[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:34]=[CH:35][C:36]=1[O:37][CH3:38])[O:21][CH2:22][CH2:23][CH2:24][N:25]1[CH2:31][CH2:30][CH2:29][CH2:28][CH:27]([CH2:32][N:8]2[CH2:7][CH2:6][C:5]3[C:10](=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=3)[C:9]2=[O:15])[CH2:26]1

Participants

3

Reactant 2

HCID 610097CorydaldineHCID 19804035HCID 19804035, compound

Product 1

HCID 19803826HCID 19803826, compound

Procedure

Prepared from 6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and N-[3-(3,4-dimethoxy-phenoxy)-propyl]-3-chloromethylhexahydro-azepine analogously to Example 2.

Sources & evidence

ORD record
ord-393f64213bd640b2adc4a2ba0c02d7c7
Source dataset
uspto-grants-1992_12
Patent number
US05175157

Reaction notes

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