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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682129Generated: October 29, 2026

Hydrochloric Acid → HCID 178475412, compound

https://huagongshe.com/reaction/1682129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178475410HCID 178475410—
CatalystPalladiumHCID 23938—
SolventEthylacetate methanolHCID 21584119—
ProductHCID 178475412HCID 17847541264%

Reaction Steps

A methanol/ethyl acetate solution of compound 41 (300 mg, 0.5 mmol) and 1N HCl (0.52 mL), containing 10% palladium on carbon, was stirred under a hydrogen atmosphere for 30 min. The suspension was filtered through a pad of Celite, and the filtrate was concentrated to afford 0.1 g (64%) of the title product as a mixture of trans and cis (3:2) isomers.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175283
Source datasetuspto-grants-1992_12
ORD IDord-892993df9cf94e198f9ec8b2fd8878f4
Source noteuspto-grants-1992_12