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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682239Generated: October 30, 2026

(2,6-Dichloropyridin-3-YL)methanamine → S-methyl-N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylisothiourea

https://huagongshe.com/reaction/1682239

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2,6-Dichloropyridin-3-YL)methanamineHCID 15477284—
ReactantN-methyl-N'-ethyl-N'-(3-pyridylmethyl)thioureaHCID 22450434—
ReactantN-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylthioureaHCID 22450473—
ProductS-methyl-N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylisothioureaHCID 22450494—

Reaction Steps

The reaction procedure of Example 13 (2) was repeated except that N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylthiourea was used in lieu of N-methyl-N'-ethyl-N'-(3-pyridylmethyl)thiourea to give S-methyl-N-ethyl-N-(6-fluoro-3-pyridylmethyl)-N'-methylisothiourea as a pale brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175301
Source datasetuspto-grants-1992_12
ORD IDord-1834d359654749e8a64233f3e7b1d326
Source noteuspto-grants-1992_12