Toluene → HCID 19937045, compound

Participants

Reaction Steps

A mixture of 3™allyl-4,5-dimethoxybenzaldehyde (10.3 g, 0.05 moles), di-(2-ethylhexyl) malonate (16.4 g, 0.05 moles), toluene (20 ml), acetic acid (0.41 ml) and piperidine (0.77 ml) is heated to reflux using a Dean Stark. After cooling, washing the toluene phase with water, drying and evaporation of the solvent, an orange-coloured oil is obtained, which is purified by chromatography on a column of silica 60 (eluent: 90:10 heptane/ethyl acetate) to give di-(2-ethylhexyl) 3-allyl-4,5-dimethoxybenzalmalonate (colourless oil, 15 g, yield=64%), which has the following characteristics:

Provenance & Evidence