HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-Mandelic acid → HCID 14901561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-Mandelic acid | HCID 11914 | — |
| Reactant | 1,1'-(Diazomethylene)bis(benzene) | HCID 61230 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 14901561 | HCID 14901561 | 91.4% |
Reaction Steps
To a solution of 25.0 g (164 mmol) of D-mandelic acid in 200 ml of ethyl acetate was added 38.9 g (164 mmol) of diphenyldiazomethane under stirring at room temperature. The completeness of reaction was monitored by TLC and the reaction mixture was concentrated. The residue was recrystallized from etherpetroleum ether to give 47.7 g of the aimed product D-5 in 91% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175341 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-0d0de96ace4447ce924217b7e9f5a24b |
| Source note | uspto-grants-1992_12 |