HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → E-2-amino-2-methyl-5-phosphono-3-pentenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | E-2-formylamino-2-methyl-5-diethylphosphono-3-pentenoic acid methyl ester | HCID 23181455 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | E-2-amino-2-methyl-5-phosphono-3-pentenoic acid | HCID 19804969 | — |
Reaction Steps
14.5 g of E-2-formylamino-2-methyl-5-diethylphosphono-3-pentenoic acid methyl ester are heated for 32 hours under nitrogen at 100°-105° in 500 ml of 4.35 N hydrochloric acid. Working up as in Example 11 yields E-2-amino-2-methyl-5-phosphono-3-pentenoic acid, m.p. 225°-226° (from water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175344 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-4eadf752ebe0406dab760c55b29f2c95 |
| Source note | uspto-grants-1992_12 |