E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester → E-2-amino-4-ethyl-5-phosphono-3-pentenoic acid

HRID 1682291Notes

Reaction equation

HRID 1682291 reaction equation
C([O:3][C:4](=[O:20])[CH:5]([NH:17]C=O)/[CH:6]=[C:7](\[CH2:15][CH3:16])/[CH2:8][P:9]([O:13]C)([O:11]C)=[O:10])C>O>[NH2:17][CH:5](/[CH:6]=[C:7](\[CH2:15][CH3:16])/[CH2:8][P:9]([OH:13])([OH:11])=[O:10])[C:4]([OH:20])=[O:3]

Participants

3

Reactant 1

HCID 86745086E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester

Product 1

HCID 86746441E-2-amino-4-ethyl-5-phosphono-3-pentenoic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Hydrolysis of E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester in a manner analogous to that described in Example 11 yields E-2-amino-4-ethyl-5-phosphono-3-pentenoic acid, m.p. 176° (H2O).

Sources & evidence

ORD record
ord-8d1cb2133af3431e85dbe142bd4dcdcf
Source dataset
uspto-grants-1992_12
Patent number
US05175344

Reaction notes

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