HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyl phosphite → E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyl phosphite | HCID 8472 | — |
| Reactant | Thionyl bromide | HCID 68176 | — |
| Reactant | 2-Formylamino-3-hydroxy-4-ethyl-4-pentenoic acid ethyl ester | HCID 21667299 | — |
| Product | E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester | HCID 86745086 | — |
Reaction Steps
Reaction of the 2-formylamino-3-hydroxy-4-ethyl-4-pentenoic acid ethyl ester with thionyl bromide and subsequent treatment with trimethyl phosphite in a manner analogous to that described in Example 1 yields E-2-formylamino-4-ethyl-5-dimethylphosphono-3-pentenoic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175344 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-d55549aefd1b4fa1a10d140c935669a6 |
| Source note | uspto-grants-1992_12 |