HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → N-benzoyl-3-methoxycaprolactam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 4-Benzoylmorpholin-3-one | HCID 12294096 | — |
| Reactant | 4-Methoxyazepan-2-one | HCID 19043822 | — |
| Reactant | 3-Chlorocaprolactam | HCID 19369318 | — |
| Product | N-benzoyl-3-methoxycaprolactam | HCID 19043821 | — |
| Product | 4-Methoxyazepan-2-one | HCID 19043822 | — |
Reaction Steps
3-Methoxycaprolactam was prepared from 3-chlorocaprolactam (prepared as described in Francis, et al. J. Am. Chem. Soc. 1958, 80, 6238) and sodium methoxide according to the method of Kondelikova, et al. (Collect. Czech. Chem. Commun. 1971, 36(9), 3391). The desired product N-benzoyl-3-methoxycaprolactam is synthesized as for N-benzoyl-3-oxomorpholine (Example I) using 3 -methoxycaprolactam in place of morpholin-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05635103 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-9aa69dbbb2814954beb15485a083d590 |
| Source note | uspto-grants-1997_06 |