(3,4-Dichlorophenyl)acetonitrile → 2,4-Diamino-5-(3,4-dichlorophenyl)-6-methoxymethyl pyrimidine

HRID 1682490Notes

Reaction equation

HRID 1682490 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11](Cl)[C:10]=2Cl)=[C:4]([CH2:18][O:19][CH3:20])[N:3]=1.[Cl:21]C1C=C(CC#N)C=CC=1Cl>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:10]=[CH:11][C:12]([Cl:21])=[C:13]([Cl:15])[CH:14]=2)=[C:4]([CH2:18][O:19][CH3:20])[N:3]=1

Participants

3

Reactant 2

HCID 76690(3,4-Dichlorophenyl)acetonitrileHCID 117391082,4-Diamino-5-(2,3,5-trichlorophenyl)-6-methoxymethylpyrimidine

Product 1

HCID 197051292,4-Diamino-5-(3,4-dichlorophenyl)-6-methoxymethyl pyrimidine

Procedure

This compound was prepared in an analogous manner to the compound of Example 2 from 3,4-dichlorophenylacetonitrile (Aldrich), mp. 204°-206° C.

Sources & evidence

ORD record
ord-5514e1996996463aaec9eeb7fa9b1b50
Source dataset
uspto-grants-1997_06
Patent number
US05635507

Reaction notes

Loading…