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HRID1682619

反应详情

EQUATION

反应方程式

HRID 1682619 的结构方程式

REACTANTS

反应物

3
结构：CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)O)C(C)C)cs1
HCID9818282

Ureidovaline

C14H23N3O3S

结构：N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1
HCID11101978

(1,3-Thiazol-5-yl)methyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate

C23H27N3O3S

结构：CC(C)[C@H](N)C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1
HCID53959563

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)c1nc(CCC(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1
HCID22862888

未命名化合物

PROCEDURE

实验过程

Using the procedure of Example 1U but replacing N-((N-methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl)-L-valine with the resultant compound of Example 31 D and replacing (2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane with the resultant compound of Example 31F provided, after purification by silica gel chromatography, the desired compound.

WORKUP

后处理

  1. customprovided
  2. customafter purification by silica gel chromatography