1-Benzyl-2-(bromomethyl)piperidine → (RS)-1-Benzyl-2-[3-(4-fluoro-phenyl)-pyrazol-1-ylmethyl]-piperidine
Reaction equation
[Br:1][CH2:2][CH:3]1[N:4]([CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH2:5][CH2:6][CH2:7][CH2:8]1.[F:16][c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][nH:25][cH:26][cH:27]2)[cH:21][cH:22]1>>[CH2:2]([CH:3]1[N:4]([CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH2:5][CH2:6][CH2:7][CH2:8]1)[n:25]1[n:24][c:23](-[c:20]2[cH:19][cH:18][c:17]([F:16])[cH:22][cH:21]2)[cH:27][cH:26]1Participants
3
Sources & evidence
- ORD record
- ord-512ade0a01694ad7b5eb989bf9ab4137
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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