HCID 54389077, compound → HCID 53754019, compound

HRID 1682971Notes

Reaction equation

HRID 1682971 reaction equation
[CH2:1]([O:3][C:4](=[O:21])[CH2:5][C:6]([C:19]#[N:20])([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:7][C:8](OCC)=[O:9])[CH3:2]>[Ni]>[CH2:1]([O:3][C:4](=[O:21])[CH2:5][C:6]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:7][C:8](=[O:9])[NH:20][CH2:19]1)[CH3:2]

Participants

3

Reactant 1

HCID 54389077HCID 54389077, compound

Product 1

HCID 53754019HCID 53754019, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared by the method of example 1.2.2 using 3-cyano-3-phenyl-pentanedioic acid diethyl ester (37 mmol) and Raney nickel (70 g) to give the title compound:

Sources & evidence

ORD record
ord-9e1cae6a51ca48ffb54de806c767cdea
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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