Benzoyl chloride, 3,4,5-trimethoxy- → 1-(3,4,5-Trimethoxybenzoyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

Participants

Reaction Steps

Prepared by the method of example 3.1 using 2-(3-phenyl-pyrrolidin-3-yl)-ethanol (10.47 mmol) and 3,4,5-trimethoxy-benzoyl chloride (10.49 mmol). Chromatographed on silica gel (200 g ) eluting with ethyl acetate and then 3% methanol in dichloromethane to give the title compound:

Provenance & Evidence