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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683007Generated: October 30, 2026

Pyridine-2-acetonitrile → Tert-butyl 4-cyano-4-(pyridin-2-YL)piperidine-1-carboxylate

https://huagongshe.com/reaction/1683007

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine-2-acetonitrileHCID 75959—
ReactantN-BOC-N,N-Bis(2-chloroethyl)amineHCID 11230235—
ProductTert-butyl 4-cyano-4-(pyridin-2-YL)piperidine-1-carboxylateHCID 53439111—

Reaction Steps

Prepare by the method of example 30.2 using 2-pyridylacetonitrile (10 mmol) and 2-chloro-N-(2-chloroethyl)-N-tert-Butoxycarbonyl-ethanamine (11 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05635510
Source datasetuspto-grants-1997_06
ORD IDord-6bea055901544213801e5e31f76b33d3
Source noteuspto-grants-1997_06