4-tert-Butylbenzoyl chloride → HCID 18333539, compound

HRID 1683025Notes

Reaction equation

HRID 1683025 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:13][CH2:12][NH:11][CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8].[C:17]([C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1)([CH3:20])([CH3:19])[CH3:18]>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:13][CH2:12][N:11]([C:25](=[O:26])[C:24]3[CH:28]=[CH:29][C:21]([C:17]([CH3:19])([CH3:18])[CH3:20])=[CH:22][CH:23]=3)[CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 184644272-(3-(3,4-Dichlorophenyl)pyrrolidin-3-yl)ethanol

Product 1

HCID 18333539HCID 18333539, compound

Procedure

Prepare by the method of example 3.1 using 2-[3-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethanol (2 mmol) and 4-tert-butyl-benzoyl chloride (2 mmol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record
ord-7aaf2828988f4bfbabe047013b2e5a90
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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