Ethyl bromoacetate → HCID 54243181, compound

HRID 1683054Notes

Reaction equation

[F:1][C:2]([F:13])([F:12])[C:3]1[CH:4]=[C:5]([CH2:9][C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.Br[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>>[CH2:19]([O:18][C:16](=[O:17])[CH2:15][C:9]([C:10]#[N:11])([C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:12])([F:13])[F:1])[CH:4]=1)[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH3:20]

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 75360m-Trifluoromethylphenylacetonitrile

Product 1

HCID 54243181HCID 54243181, compound

Procedure

Prepare by the method of example 1.1.2 using 3-trifluoromethyl-phenylacetonitrile (0.161 mol) and ethyl bromoacetate (0.325 mol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record: ord-f479cf7bc6784dd78a7f3e8782cf39ce
Source dataset: uspto-grants-1997_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05635510

Reaction notes

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