Benzoyl chloride, 3,4,5-trimethoxy- → HCID 18333403, compound

HRID 1683059Notes

Reaction equation

HRID 1683059 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([CH2:11][CH2:12][OH:13])[CH2:10][CH2:9][NH:8][CH2:7]1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:22]=[C:23]([O:27][CH3:28])[C:24]=1[O:25][CH3:26])[C:19](Cl)=[O:20]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([CH2:11][CH2:12][OH:13])[CH2:10][CH2:9][N:8]([C:19](=[O:20])[C:18]2[CH:17]=[C:16]([O:15][CH3:14])[C:24]([O:25][CH3:26])=[C:23]([O:27][CH3:28])[CH:22]=2)[CH2:7]1

Participants

3

Reactant 2

HCID 78282Benzoyl chloride, 3,4,5-trimethoxy-HCID 18333529HCID 18333529, compound

Product 1

HCID 18333403HCID 18333403, compound

Procedure

Prepare by the method of example 3.1 using 2-[3-(thiophen-2-yl)-pyrrolidin-3-yl]-ethanol (23 mmol) and 3,4,5-trimethoxy-benzoyl chloride (23 mmol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record
ord-02b78060fd0d45cea8c4722a9f58c733
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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