Benzoyl chloride, 3,4,5-trimethoxy- → HCID 54510264, compound

HRID 1683065Notes

Reaction equation

HRID 1683065 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([CH2:13][CH2:14][OH:15])[CH2:12][CH2:11][NH:10][CH2:9]1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:24]=[C:25]([O:29][CH3:30])[C:26]=1[O:27][CH3:28])[C:21](Cl)=[O:22]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([CH2:13][CH2:14][OH:15])[CH2:12][CH2:11][N:10]([C:21](=[O:22])[C:20]2[CH:19]=[C:18]([O:17][CH3:16])[C:26]([O:27][CH3:28])=[C:25]([O:29][CH3:30])[CH:24]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 78282Benzoyl chloride, 3,4,5-trimethoxy-HCID 53867603HCID 53867603, compound

Product 1

HCID 54510264HCID 54510264, compound

Procedure

Prepare by the method of example 3.1 using 2-[3-(2-fluoro-phenyl)-pyrrolidin-3-yl]-ethanol (23 mmol) and 3,4,5-trimethoxy-benzoyl chloride (23 mmol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record
ord-bda2889dd1ec44a0b52d907faa99056a
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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