Ethyl bromoacetate → HCID 54564589, compound

HRID 1683068Notes

Reaction equation

HRID 1683068 reaction equation
[Si:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16]#[N:17])=[CH:11][CH:10]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Br[CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[CH2:23]([O:22][C:20](=[O:21])[CH2:19][C:15]([C:16]#[N:17])([C:12]1[CH:11]=[CH:10][C:9]([O:8][Si:1]([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2])=[CH:14][CH:13]=1)[CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH3:24]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 183335824-(Tert-butyldimethylsilyloxy)-phenyl-acetonitrile

Product 1

HCID 54564589HCID 54564589, compound

Procedure

Prepare by the method of example 1.1.2 using 4-(tert-butyldimethylsilyloxy)-phenyl-acetonitrile (0.161 mol) and ethyl bromoacetate (0.325 mol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record
ord-73793b6d14fe4424a3b3a2c46dcbe4c8
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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