Benzoyl chloride, 3,4,5-trimethoxy- → HCID 18333256, compound

HRID 1683069Notes

Reaction equation

HRID 1683069 reaction equation
[Si:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2([CH2:21][CH2:22][OH:23])[CH2:19][C:18](=O)[NH:17][CH2:16]2)=[CH:11][CH:10]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:32]=[C:33]([O:37][CH3:38])[C:34]=1[O:35][CH3:36])[C:29](Cl)=[O:30]>>[Si:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2([CH2:21][CH2:22][OH:23])[CH2:19][CH2:18][N:17]([C:29](=[O:30])[C:28]3[CH:27]=[C:26]([O:25][CH3:24])[C:34]([O:35][CH3:36])=[C:33]([O:37][CH3:38])[CH:32]=3)[CH2:16]2)=[CH:13][CH:14]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 78282Benzoyl chloride, 3,4,5-trimethoxy-HCID 67697508HCID 67697508, compound

Product 1

HCID 18333256HCID 18333256, compound

Procedure

Prepare by the method of example 3.1 using 2-[3-[4-(tert-butyldimethylsilyloxy)-phenyl]-5-oxo-pyrrolidin-3-yl]-ethanol (23 mmol) and 3,4,5-trimethoxy-benzoyl chloride (23 mmol). Chromatograph on silica gel to give the title compound.

Sources & evidence

ORD record
ord-43ded4159ee84ab38acba27926270cd1
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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