2-Thienylacetonitrile → HCID 54508573, compound

HRID 1683078Notes

Reaction equation

HRID 1683078 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]#[N:8].Cl[CH2:10][CH2:11][N:12]([CH2:20][CH2:21]Cl)[C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14]>>[C:16]([O:15][C:13]([N:12]1[CH2:20][CH2:21][C:6]([C:7]#[N:8])([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)[CH2:10][CH2:11]1)=[O:14])([CH3:19])([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 728802-ThienylacetonitrileHCID 11230235N-BOC-N,N-Bis(2-chloroethyl)amine

Product 1

HCID 54508573HCID 54508573, compound

Procedure

Prepare by the method of example 30.2 using 2-thiopheneacetonitrile (10 mmol) and 2-chloro-N-(2-chloroethyl)-N-tert-Butoxycarbonyl-ethanamine (11 mmol). Purify to give the title compound.

Workup

  1. customPurify

Sources & evidence

ORD record
ord-8172c72e50514884b36acb4c30850425
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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