HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(Thiophen-2-yl)-piperidine-4-carboxylic acid amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 1-Tert-butoxycarbonyl-4-(thiophen-2-yl)-piperidine-4-carboxylic acid amide | HCID 54416848 | — |
| Product | 4-(Thiophen-2-yl)-piperidine-4-carboxylic acid amide hydrochloride | HCID 67560108 | — |
Reaction Steps
Prepare by the method of example 20.10 using 1-tert-butoxycarbonyl-4-(thiophen-2-yl)-piperidine-4-carboxylic acid amide (3 mmol) and HCl in dioxane (40 mmol, 4N) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05635510 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-fac21a07b0f94382909c8cad98794d19 |
| Source note | uspto-grants-1997_06 |