(3-Methoxyphenyl)acetonitrile → HCID 67562153, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.Cl.[Cl:13][CH2:14][CH2:15][N:16]([CH2:24][CH2:25]Cl)[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[ClH:13].[CH2:17]([N:16]1[CH2:24][CH2:25][C:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)([C:10]#[N:11])[CH2:14][CH2:15]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1Participants
3
Procedure
Prepare by the method of example 74.1 using 3-methoxyphenyl-acetonitrile (3.68 g, 25 mmol) and N,N-bis(2-chloroethyl)-N-benzylamine hydrochloride (7.05 g, 26.25 mmol) to the title compound.
Sources & evidence
- ORD record
- ord-c6754d0a3da24bb1a5111bfde5012cb7
- Source dataset
- uspto-grants-1997_06
- Patent number
- US05635510
Reaction notes
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