4-(Trifluoromethyl)phenylacetonitrile → HCID 53826943, compound

HRID 1683127Notes

Reaction equation

HRID 1683127 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]#[N:11])=[CH:5][CH:4]=1.Cl.Cl[CH2:16][CH2:17][N:18]([CH2:26][CH2:27]Cl)[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([N:18]1[CH2:26][CH2:27][C:9]([C:6]2[CH:5]=[CH:4][C:3]([C:2]([F:12])([F:13])[F:1])=[CH:8][CH:7]=2)([C:10]#[N:11])[CH2:16][CH2:17]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 753594-(Trifluoromethyl)phenylacetonitrileHCID 2777881N,N-Bis(2-chloroethyl)benzylamine hydrochloride

Product 1

HCID 53826943HCID 53826943, compound

Procedure

Prepare by the method of example 76.1 using 4-trifluoromethylphenyl-acetonitrile (1.5 g, 8.1 mmol) and N,N-bis(2-chloroethyl)-N-benzylamine hydrochloride (1.9 g, 8.1 mmol) to give the title compound.

Sources & evidence

ORD record
ord-fe6039e4fad84ffd9c2f9c482892b9c3
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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