Diethyl Oxalate → HCID 3412732, compound

Participants

Reaction Steps

13.0 g of N,N-diethyl-1,3-diaminopropane were added to 70 ml of diethyl oxalate with stirring at room temperature over a period of 20 minutes. After stirring at room temperature for 2 hours, excess diethyl oxalate was distilled off under reduced pressure to obtain 21.7 g of N,N-diethyl-N'-ethoxalyl-1,3-diaminopropane as an oily product. 6.90 g of this oily product and 3.99 g of 3-(2-methoxyethoxy)propylamine were dissolved in 30 ml of methanol and the solution was heated under reflux for 1 hour. The solvent was distilled off under reduced pressure to obtain 9.51 g of Compound B-1 as an oily product.

Provenance & Evidence