Diethyl Ether → HCID 19042879, compound

Participants

Reaction Steps

2-(2-Chloro-3-phenoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole (2.80 g, 9.28 mmol) was heated with methyl iodide (1.8 mL) in nitromethane (4.0 mL) for 24 hr, (bath temp ca 70° C.). The brown solution was allowed to cool and Et2O was added until a slight cloudiness was observed. Crystallization commenced almost immediately and the mixture was allowed to stand in the freezer overnight. Large off-white crystals of the product: 2-(2-chloro-3-phenoxyphenyl)-3,4,4-trimethyl-4,5-dihydrooxazolium iodide were obtained. 3.51 g, (85%).

Provenance & Evidence