Dichloromethane → HCID 13679341, compound

HRID 1683357Notes

Reaction equation

[C:1]1([CH2:7][CH2:8][C:9](=[O:11])[CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:13]Cl>>[O:11]1[C:9]([CH3:13])([CH2:8][CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:10]1

Participants

Reactant 2

HCID 6344Dichloromethane

HCID 17355Benzyl acetone

Product 1

HCID 13679341HCID 13679341, compoundYield 72%

Procedure

Using the same conditions described in Example 5, but using dichloromethane as the extraction solvent, 4-phenyl-2-butanone (22.2 g, 0.15 mole) yielded an orange oil; 1,2-epoxy-2-methyl-4-phenylbutane (19.8g, 72% yield of theory). 1H NMR (CDCl3 /TMS): δ 1.3(s,3H, CH3); 1.6-2.1(m, 2H), 2.-2.8(m, 4H); 6.8-7.4(m, 5H, aromatic H).

Workup

customyielded an orange oil

Sources & evidence

ORD record: ord-3a167da67f434f47a9a1d59e9c189f75
Source dataset: uspto-grants-1997_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05637727

Reaction notes

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